Fluorescent biosensors for real-time tracking of post-translational modification dynamics
نویسندگان
چکیده
منابع مشابه
Molecular Dynamics Simulation of Phosphorylated KID Post-Translational Modification
BACKGROUND Kinase-inducible domain (KID) as transcriptional activator can stimulate target gene expression in signal transduction by associating with KID interacting domain (KIX). NMR spectra suggest that apo-KID is an unstructured protein. After post-translational modification by phosphorylation, KID undergoes a transition from disordered to well folded protein upon binding to KIX. However, th...
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ژورنال
عنوان ژورنال: Current Opinion in Chemical Biology
سال: 2009
ISSN: 1367-5931
DOI: 10.1016/j.cbpa.2009.07.009